METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS

METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS

The invention provides methods of making immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions generated by such methods. La invención proporciona métodos de preparación de células efectoras inmunitarias (por ejemplo, células T, célul...

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Hauptverfasser: ENGELS Boris, HACK Anniesha, KOSHY Sandeep Tharian, BARDROFF Michael, GREENE Michael R, PRICE Andrew, LIM Hyungwook, GRANDA Brian Walter, MILLER Sandra, DRANOFF Glenn, PRATICO Elizabeth Dorothy, KODRASI Olja, BONDANZA Attilio, GUIMARAES Carla, JAYASHANKAR Shyamali, ZHU Xu, CEBE Regis, RAYO Amy, BROGDON Jennifer, SOHONI Akash, YANG Jennifer, TREANOR Louise, STEIN Andrew Marc
Format: Patent
Sprache:eng ; spa
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The invention provides methods of making immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions generated by such methods. La invención proporciona métodos de preparación de células efectoras inmunitarias (por ejemplo, células T, células NK) que expresan un receptor de antígeno quimérico (CAR), y composiciones generadas mediante tales métodos.