RAPAMYCIN ANALOGS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same. The present invention relates to compounds and methods useful for modulating mTORC1 activity. The invention also provides pharmaceutically acceptable compositions comprising provided compounds of the prese...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: O'NEILL David John, KANG Seong Woo Anthony, SAIAH Eddine
Format: Patent
Sprache:eng ; spa
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Beschreibung
Zusammenfassung:The present invention provides compounds, compositions thereof, and methods of using the same. The present invention relates to compounds and methods useful for modulating mTORC1 activity. The invention also provides pharmaceutically acceptable compositions comprising provided compounds of the present invention and methods of using such compositions in the treatment of various disorders. La presente invención proporciona compuestos, composiciones de estos y métodos para usarlos. La presente invención se relaciona con compuestos y métodos útiles para modular la actividad de mTORC1. La invención también proporciona composiciones farmacéuticamente aceptables que comprenden compuestos proporcionados de la presente invención y métodos para usar tales composiciones en el tratamiento de diversos trastornos.