BICYCLIC AMINES AS CDK2 INHIBITORS

The present application provides bicyclic amines that are inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same. La presente solicitud proporciona aminas bicíclicas que inhiben la cinasa dependiente de ciclina 2...

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Hauptverfasser: FAVATA Margaret, YE Min, QIAN Ding-quan, YAO Wenqing, WU Liangxing, LO Yvonne, WINTERTON Sarah, XIAO Kaijiong, LI Zhenwu, XU Meizhong, HUMMEL Joshua, YE Yingda, CHEN Yingnan
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creator FAVATA Margaret
YE Min
QIAN Ding-quan
YAO Wenqing
WU Liangxing
LO Yvonne
WINTERTON Sarah
XIAO Kaijiong
LI Zhenwu
XU Meizhong
HUMMEL Joshua
YE Yingda
CHEN Yingnan
description The present application provides bicyclic amines that are inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same. La presente solicitud proporciona aminas bicíclicas que inhiben la cinasa dependiente de ciclina 2 (CDK2), así como composiciones farmacéuticas de estas, y métodos de tratamiento del cáncer mediante su uso.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title BICYCLIC AMINES AS CDK2 INHIBITORS
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