BICYCLIC AMINES AS CDK2 INHIBITORS

BICYCLIC AMINES AS CDK2 INHIBITORS

The present application provides bicyclic amines that are inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same. La presente solicitud proporciona aminas bicíclicas que inhiben la cinasa dependiente de ciclina 2...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FAVATA Margaret, YE Min, QIAN Ding-quan, YAO Wenqing, WU Liangxing, LO Yvonne, WINTERTON Sarah, XIAO Kaijiong, LI Zhenwu, XU Meizhong, HUMMEL Joshua, YE Yingda, CHEN Yingnan
Format: Patent
Sprache:eng ; spa
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present application provides bicyclic amines that are inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same. La presente solicitud proporciona aminas bicíclicas que inhiben la cinasa dependiente de ciclina 2 (CDK2), así como composiciones farmacéuticas de estas, y métodos de tratamiento del cáncer mediante su uso.