A NOVEL COMPLEX FORMED BETWEEN THE FLAVIVIRAL NON-STRUCTURAL NS1 PROTEIN AND PLASMA LIPOPROTEINS

The invention concerns methods for early detection, monitoring and prognosis of a flavivirus-induced infection, comprising the detection of a complex formed by the flavivirus non-structural glycoprotein NS1 and plasma lipoprotein particles in a biological sample during the clinical phase of the infe...

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Hauptverfasser: VOSS James, GIAI GIANETTO Quentin, FLAMAND Marie, REY Félix, MATONDO Mariette, PARK Kyu- Ho Paul, DUSSART Philippe, DUONG Veasna, TAMIETTI Carole, DELLAROLE Mariano, COULIBALY Fasséli, BONTEMS François, SAKUNTABHAI Anavaj, BENFRID Souheyla
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The invention concerns methods for early detection, monitoring and prognosis of a flavivirus-induced infection, comprising the detection of a complex formed by the flavivirus non-structural glycoprotein NS1 and plasma lipoprotein particles in a biological sample during the clinical phase of the infection. La invención se refiere a métodos para la detección prematura, monitoreo y pronóstico de una infección inducida por flavivirus, comprendiendo la detección de un complejo formado por la glicoproteína no estructural NSI de flavivirus y partículas de lipoproteína de plasma en una muestra biológica durante la fase clínica de la infección.