EXTRACELLULAR VESICLE COMPOSITIONS

The present disclosure relates to compositions for the storage and administration of extracellular vesicles (e.g., exosomes) that can comprise a scaffold protein and one or more (e.g., 1, 2, 3, 4, 5 or more) exogenous biologically active moieties. Also provided herein are methods for producing the e...

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Bibliographische Detailangaben
Hauptverfasser:	O'NEIL Conlin, DOHERTY Mike, BOURDEAU Raymond, HARRISON Rane, NOYES Aaron
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure relates to compositions for the storage and administration of extracellular vesicles (e.g., exosomes) that can comprise a scaffold protein and one or more (e.g., 1, 2, 3, 4, 5 or more) exogenous biologically active moieties. Also provided herein are methods for producing the exosomes and methods for using the exosomes to treat and/or prevent a range of medical disorders. La presente descripción se refiere a composiciones para el almacenamiento y la administración de vesículas extracelulares (p. ej., exosomas) que pueden comprender una proteína de andamiaje y uno o más (p. ej., 1, 2, 3, 4, 5 o más) restos exógenos biológicamente activos. También se proporcionan en este documento métodos para producir los exosomas y métodos para usar los exosomas para tratar y/o prevenir una variedad de trastornos médicos.