4-1BB AND OX40 BINDING PROTEINS AND RELATED COMPOSITIONS AND METHODS, ANTIBODIES AGAINST 4-1BB, ANTIBODIES AGAINST OX40

4-1BB AND OX40 BINDING PROTEINS AND RELATED COMPOSITIONS AND METHODS, ANTIBODIES AGAINST 4-1BB, ANTIBODIES AGAINST OX40

The present disclosure provides antibodies that specifically bind to 4-1BB and/or OX40, including bispecific antibodies that bind to 4-1BB and OX40, and compositions comprising such antibodies. Also provided are methods for treating disorders, such as cancer, using such antibodies and compositions....

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Bibliographische Detailangaben
Hauptverfasser: HERNANDEZ-HOYOS Gabriela, VAN CITTERS Danielle, MISHER Lynda, BIENVENUE David Leonard, NELSON Michelle Hase, PAVLIK Peter
Format: Patent
Sprache:eng ; spa
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present disclosure provides antibodies that specifically bind to 4-1BB and/or OX40, including bispecific antibodies that bind to 4-1BB and OX40, and compositions comprising such antibodies. Also provided are methods for treating disorders, such as cancer, using such antibodies and compositions. La presente descripción proporciona anticuerpos que se unen específicamente a 4-1BB y/u OX40, que incluyen anticuerpos biespecíficos que se unen a 4-1BB y OX40, y composiciones que comprenden tales anticuerpos. También se proporcionan métodos para tratar trastornos, tales como el cáncer, usando tales anticuerpos y composiciones.