HYDROPHOBIC PEPTIDE SALTS FOR EXTENDED RELEASE COMPOSITIONS

The present disclosure, relates, in general, to hydrophobic salts of hydrophilic peptides that form low solubility materials in aqueous solutions and are capable of extended or sustained release of the peptide component when administered to a subject. Hydrophobic salts of C-type natriuretic peptides...

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Bibliographische Detailangaben
Hauptverfasser: LABER Joshua, CHOU Joyce, ESTRADA Karol, BATTU Sunil Kumar, LEBOWITZ Jonathan, ANG Jake
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The present disclosure, relates, in general, to hydrophobic salts of hydrophilic peptides that form low solubility materials in aqueous solutions and are capable of extended or sustained release of the peptide component when administered to a subject. Hydrophobic salts of C-type natriuretic peptides and uses thereof are also disclosed. La presente divulgación se refiere, en general, a sales hidrófobas de péptidos hidrófilos que forman materiales de baja solubilidad en soluciones acuosas y son capaces de liberación prolongada o sostenida del componente peptídico cuando se administran a un sujeto. También se divulgan sales hidrófobas de péptidos natriuréticos tipo C y usos de estas.