AZACITIDINE IN COMBINATION WITH VENETOCLAX, GILTERITINIB, MIDOSTAURIN OR OTHER COMPOUNDS FOR TREATING LEUKEMIA OR MYELODYSPLASTIC SYNDROME

Provided herein are methods for using 5-azacytidine in combination with one or more additional agents to treat diseases and disorders including acute myeloid or myelogenous leukemia (AML). Other disease and disorders those associated with abnormal cell proliferation, myelodysplastic syndromes (MDS),...

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Hauptverfasser: DUNSHEE Diana R, LOPES DE MENEZES Daniel E, DAI Yumin, BEACH Cl, ROSE Shelonitda, MACBETH Kyle, FRATTINI Mark, JANG Jessica
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:Provided herein are methods for using 5-azacytidine in combination with one or more additional agents to treat diseases and disorders including acute myeloid or myelogenous leukemia (AML). Other disease and disorders those associated with abnormal cell proliferation, myelodysplastic syndromes (MDS), abnormal cell proliferation, hematologic disorders, and immune disorders, among others. En el presente documento se proporcionan métodos para usar 5-azacitidina en combinación con uno o más agentes adicionales para tratar enfermedades y trastornos que incluyen leucemia mieloide o mielógena aguda (LMA). Otras enfermedades y trastornos asociados con proliferación celular anormal, síndromes mielodisplásicos (SMD), proliferación celular anormal, trastornos hematológicos y trastornos inmunitarios, entre otros.