COMPOSITIONS AND METHODS FOR TREATMENT OF HEMOCHROMATOSIS

This application provides polynucleotides comprising a coding sequence for a functionally active hereditary hemochromatosis protein (HFE) or a functionally active fragment thereof. The invention further provides compositions comprising said polynucleotides and their use in methods of preventing or t...

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Bibliographische Detailangaben
Hauptverfasser:	DAUGHERTY Sean Christopher, CARSON Rosaline Do, CATALDO Jason Robert, WONG Timothy Preston
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	This application provides polynucleotides comprising a coding sequence for a functionally active hereditary hemochromatosis protein (HFE) or a functionally active fragment thereof. The invention further provides compositions comprising said polynucleotides and their use in methods of preventing or treating hemochromatosis in a subject. La presente solicitud proporciona polinucleótidos que comprenden una secuencia codificante para una proteína funcionalmente activa de hemocromatosis hereditaria (HFE) o un fragmento funcionalmente activo de la misma. La invención proporciona además composiciones que comprenden dichos polinucleótidos y su uso en métodos para prevenir o tratar la hemocromatosis en un sujeto.