TECHNOLOGIES USEFUL FOR OLIGONUCLEOTIDE PREPARATION

TECHNOLOGIES USEFUL FOR OLIGONUCLEOTIDE PREPARATION

Among other things, the present disclosure provides technologies for oligonucleotide preparation, particularly chirally controlled oligonucleotide preparation, which technologies provide greatly improved crude purity and yield, and significantly reduce manufacturing costs. Entre otras cosas, la pres...

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Bibliographische Detailangaben
Hauptverfasser: ALAM Mohammed Rowshon, SHIMIZU Mamoru, KANDASAMY Pachamuthu, BOMMINENI Gopal Reddy, VARGEESE Chandra, BOWMAN Keith Andrew, DIVAKARAMENON Sethumadhavan, KUMARASAMY Jayakanthan, BHATTARAI Bijay Tilak, STANDLEY Stephany Michelle, BUTLER David Charles Donnell
Format: Patent
Sprache:eng ; spa
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Beschreibung
Zusammenfassung:Among other things, the present disclosure provides technologies for oligonucleotide preparation, particularly chirally controlled oligonucleotide preparation, which technologies provide greatly improved crude purity and yield, and significantly reduce manufacturing costs. Entre otras cosas, la presente divulgación proporciona tecnologías para la preparación de oligonucleótidos, particularmente para la preparación de oligonucleótidos controlada quiralmente, proporcionando las tecnologías una pureza en bruto y un rendimiento enormemente mejorados, y reduciendo significativamente los costes de fabricación.