METHODS OF TREATING MULTIPLE MYELOMA

The present disclosure provides methods for treating multiple myeloma (such as refractory multiple myeloma or relapsed and refractory multiple myeloma) in an individual who received at least two prior therapies for multiple myeloma. The methods comprise administering to the individual an anti-CD38 a...

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Bibliographische Detailangaben
Hauptverfasser:	AUDAT Heloise, HUILLE Sylvain, CAMPANA ZAMBRANO Frank, LE-GUENNEC Solenn, MANACHE-ALBERICI Lucie, BONESTEBE Audrey
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure provides methods for treating multiple myeloma (such as refractory multiple myeloma or relapsed and refractory multiple myeloma) in an individual who received at least two prior therapies for multiple myeloma. The methods comprise administering to the individual an anti-CD38 antibody, pomalidomide, and dexamethasone. Also provided are methods of improving renal impairment in an individual having multiple myeloma. La presente descripción proporciona métodos para tratar el mieloma múltiple (tal como mieloma múltiple refractario o mieloma múltiple recidivante y refractario) en un individuo que recibió al menos dos terapias anteriores para el mieloma múltiple. Los métodos comprenden administrar al individuo un anticuerpo anti-CD38, pomalidomida, y dexametasona. También se proporcionan métodos para mejorar el deterioro renal en un individuo que tiene mieloma múltiple.