SOLID FORMS COMPRISING (S)-4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL) -1-OXOISOINDOLIN-4-YL)OXY)METHYL) BENZYL)PIPERAZIN-1-YL)-3-FLUORO BENZONITRILE AND SALTS THEREOF, AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME

SOLID FORMS COMPRISING (S)-4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL) -1-OXOISOINDOLIN-4-YL)OXY)METHYL) BENZYL)PIPERAZIN-1-YL)-3-FLUORO BENZONITRILE AND SALTS THEREOF, AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME

Provided herein are formulations, processes, solid forms and methods of use relating to salts of and solid forms comprising free base or salts of (S)-4-(4-(4-(((2-(2,6- dioxopiperidin-3-yl)-l-oxoisoindolin-4-yl)oxy)methyl)benzyl)pip erazin-l-yl)-3- fluorobenzonitrile. Se proporcionan en la presente...

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Bibliographische Detailangaben
Hauptverfasser: HUANG Lianfeng, MAN Hon- Wah, TAVARES-GRECO Paula A, TSOU Nancy Nienhua, FERRETTI Antonio C, WU Wenju, ARTMAN III Gerald D, YIN Zhiwei, JAIN Udaykumar
Format: Patent
Sprache:eng ; spa
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Provided herein are formulations, processes, solid forms and methods of use relating to salts of and solid forms comprising free base or salts of (S)-4-(4-(4-(((2-(2,6- dioxopiperidin-3-yl)-l-oxoisoindolin-4-yl)oxy)methyl)benzyl)pip erazin-l-yl)-3- fluorobenzonitrile. Se proporcionan en la presente formulaciones, procesos, formas sólidas y métodos de uso relacionados con sales y formas sólidas que comprenden bases libres o sales de (S)-4-(4-(4-(((2-(2,6- dioxopiperidin-3-il)-1-oxoisoindolin-4-il)oxi)metil)bencil)pipera zin-1-il)-3-fluorobenzonitrilo.