INHIBITORS OF APOL1 AND METHODS OF USING SAME

The disclosure provides at least one entity chosen from compounds of formula (I), solid state forms of the same, compositions comprising the same, and methods of using the same, including use in treating focal segmental glomerulosclerosis (FSGS) and/or non-diabetic kidney disease (NDKD). La descripc...

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Bibliographische Detailangaben
Hauptverfasser:	NICOLAS Olivier, SAYEGH Camil, NANTHAKUMAR Suganthini S, SENTER Timothy J, LEDFORD Brian, HAMEL Martine, BRODNEY Michael, SHRESTHA Muna, DORSCH Warren A, WANG Tiansheng, ROSE Peter, FORTIER Anne, GAGNON Kevin, CAO Jingrong, HU Kan - Nian, DAKIN Leslie A, COME Jon H, WITKOS Faith, MEDEK Ales, DENIS Francois, SHI Yi, KRUEGER Elaine B
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The disclosure provides at least one entity chosen from compounds of formula (I), solid state forms of the same, compositions comprising the same, and methods of using the same, including use in treating focal segmental glomerulosclerosis (FSGS) and/or non-diabetic kidney disease (NDKD). La descripción proporciona al menos una entidad seleccionada de compuestos de la fórmula (I), formas en estado sólido de ellos, composiciones que los comprenden y métodos que los usan, incluyendo el uso en el tratamiento de glomeruloesclerosis segmentaria focal (FSGS) y/o enfermedad renal no diabética (NDKD).