ALK5 INHIBITORS

The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5. La presente divulgación proporciona inhibidores de la cinasa 5 similar al receptor de activina (ALK...

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Hauptverfasser: KOZAK Jennifer, HUGHES Adam D, OWENS Christina, SULLIVAN Steven D. E, KULYK Svitlana
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creator KOZAK Jennifer
HUGHES Adam D
OWENS Christina
SULLIVAN Steven D. E
KULYK Svitlana
description The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5. La presente divulgación proporciona inhibidores de la cinasa 5 similar al receptor de activina (ALK5). También se describen métodos para modular la actividad de ALK5 y métodos de tratamiento de trastornos mediados por ALK5.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ALK5 INHIBITORS
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