ALK5 INHIBITORS

The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5. La presente divulgación proporciona inhibidores de la cinasa 5 similar al receptor de activina (ALK...

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Bibliographische Detailangaben
Hauptverfasser:	KOZAK Jennifer, HUGHES Adam D, OWENS Christina, SULLIVAN Steven D. E, KULYK Svitlana
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5. La presente divulgación proporciona inhibidores de la cinasa 5 similar al receptor de activina (ALK5). También se describen métodos para modular la actividad de ALK5 y métodos de tratamiento de trastornos mediados por ALK5.