QUATERNARY AMMONIUM SALTS AS INHIBITORS OF TRIMETHYLAMINE PRODUCTION

Provided are compounds that can inhibit pathogenic, bacterial metabolite production and conjugates of the same. Also provided are pharmaceutical compositions comprising the same and methods of using the same. Se proporcionan compuestos que pueden inhibir la producción de metabolitos patógenos, bacte...

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Hauptverfasser: PROUDFOOT John, BRIGGS Timothy, TEFFERA Yohannes, LIU Jenny, ROSS Cheri, YASUDA Koji, BILLINGS Gabriel, GUNASEKERA Dinara Shashanka, MARTINEZ-DEL CAMPO Ana, LAFRANCE Danny, BOGART Elijah, DOUD Devin Forest Reed, PECK Spencer Cory, NUDEL Kathleen, AJAYI Kehinde, TAYLOR Steven
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:Provided are compounds that can inhibit pathogenic, bacterial metabolite production and conjugates of the same. Also provided are pharmaceutical compositions comprising the same and methods of using the same. Se proporcionan compuestos que pueden inhibir la producción de metabolitos patógenos, bacterianos y conjugados de los mismos. Además, se proporcionan composiciones farmacéuticas que comprenden los mismos y métodos para usarlos.