TOPICAL TREATMENT OF IMMUNE CHECKPOINT INHIBITOR INDUCED DIARRHOEA, COLITIS OR ENTEROCOLITIS USING ANTIBODIES AND FRAGMENTS THEREOF

TOPICAL TREATMENT OF IMMUNE CHECKPOINT INHIBITOR INDUCED DIARRHOEA, COLITIS OR ENTEROCOLITIS USING ANTIBODIES AND FRAGMENTS THEREOF

The present invention relates to the therapeutic topical use of compositions containing antibody molecules or functional fragments or derivatives specific to tumour necrosis factor alpha (TNFα), for treating or preventing immune checkpoint (ICP) inhibitor-induced adverse events. La presente invenci...

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Bibliographische Detailangaben
Hauptverfasser: BRUNO Cristina, GERSTNER Ortrud, BRAVO Roberto, FURRER Esther Maria, SPLEISS Johannes, VARUM Felipe, NEDELJKOVIC PROTIC Marijana
Format: Patent
Sprache:eng ; spa
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to the therapeutic topical use of compositions containing antibody molecules or functional fragments or derivatives specific to tumour necrosis factor alpha (TNFα), for treating or preventing immune checkpoint (ICP) inhibitor-induced adverse events. La presente invención se refiere al uso tópico terapéutico de composiciones que contienen moléculas de anticuerpos o fragmentos funcionales o derivados específicos del factor de necrosis tumoral alfa (TNFa), para tratar o prevenir eventos adversos inducidos por inhibidores de puntos de control inmunológico (ICP).