HUMANIZED ANTI-SIRPa ANTIBODIES

The present invention relates to humanized antibodies against SIRPa that are suitable for use in anti-cancer therapy. The invention further relates to the use of the humanized anti-SIRPa antibodies in the treatment of human solid tumours and haematological malignancies, optionally in combination wit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser:	VERHEIJDEN Gijsbertus Franciscus Maria
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to humanized antibodies against SIRPa that are suitable for use in anti-cancer therapy. The invention further relates to the use of the humanized anti-SIRPa antibodies in the treatment of human solid tumours and haematological malignancies, optionally in combination with further anti-cancer therapeutics. La presente invención se refiere a anticuerpos humanizados contra SIRPa que son adecuados para usarse en terapia anti-cáncer; la invención se refiere además al uso de los anticuerpos anti-SIRPa humanizados en el tratamiento de tumores sólidos humanos y malignidades hematológicas, opcionalmente en combinación con agentes terapéuticos anti-cáncer adicionales.