PHYTOPHARMACOLOGICAL COMPOSITION OF THE HYDROALCOHOLIC EXTRACT OF THE ROOT OF SECHIUM EDULE WITH HEPATOPROTECTIVE EFFECT

The present invention relates to the oral administration of Rse-HA prevented steatosis (fatty liver), hepatomegaly, hypertriglyceridemia, increased adipose tissue, hepatocellular necrosis, inflammation, and liver fibrosis, characteristics of Non-Alcoholic Steatohepatitis, induced by the chronic appl...

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Hauptverfasser: JIMÉNEZ FERRER Jesús Enrique, ALVARADO OJEDA Zimri Aziel, COSTET MEJÍA Alejandro, ARELLIN ROSAS Gerardo, HERNÁNDEZ GARCÍA Brenda, FRAGOSO GONZÁLEZ Gladis Del Carmen, ROSAS SALGADO Gabriela, CASTRO MARTÍNEZ Gabriela, ZAMILPA ÁLVAREZ Alejandro, TREJO MORENO Celeste
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The present invention relates to the oral administration of Rse-HA prevented steatosis (fatty liver), hepatomegaly, hypertriglyceridemia, increased adipose tissue, hepatocellular necrosis, inflammation, and liver fibrosis, characteristics of Non-Alcoholic Steatohepatitis, induced by the chronic application of Angiotensin II in the mouse. La administración oral del Rse-HA evitó la esteatosis (hígado graso), hepatomegalia, hipertrigliceridemia, el aumento del tejido adiposo, la necrosis hepatocelular, la inflamación y la fibrosis hepática, características de la Esteatohepatitis No Alcohólica, inducida por la aplicación crónica de Angiotensina II en ratón.