DOSING

The present invention relates to a method of treating cancer in a human in need thereof, the method comprising administering to the human an agonist ICOS binding protein or antigen binding portion thereof at a dose of about 0.08 mg to about 240 mg and administering to the human a PD1 antagonist. La...

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Bibliographische Detailangaben
Hauptverfasser: MAYES Patrick, PAUL Elaine Marie, ELLIS Catherine E, KATZ Jessica
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The present invention relates to a method of treating cancer in a human in need thereof, the method comprising administering to the human an agonist ICOS binding protein or antigen binding portion thereof at a dose of about 0.08 mg to about 240 mg and administering to the human a PD1 antagonist. La presente invención se refiere a un método de tratamiento de cáncer en un humano en necesidad del mismo, el método comprende administrar al humano una proteína agonista de unión a ICOS o porción de unión a antígeno de la misma a una dosis de cerca de 0.08 5 mg a cerca de 240 mg y administrar al humano un antagonista de PD1.