DOUBLE-STRANDED RIBONUCLEIC ACID INHIBITING EXPRESSION OF COMPLEMENT C5

Disclosed is a double-stranded ribonucleic acid that comprises a combination of a sense strand with an antisense strand, said combination being selected from the group consisting of SEQ ID NOS: 159 and 160, SEQ ID NOS: 141 and 142, SEQ ID NOS: 143 and 144, SEQ ID NOS: 145 and 146, SEQ ID NOS: 147 an...

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Hauptverfasser: MOTOI Sotaro, TAKAHASHI Yoshinori, SUZUKI Yuta, TAHARA Kazuhiro
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:Disclosed is a double-stranded ribonucleic acid that comprises a combination of a sense strand with an antisense strand, said combination being selected from the group consisting of SEQ ID NOS: 159 and 160, SEQ ID NOS: 141 and 142, SEQ ID NOS: 143 and 144, SEQ ID NOS: 145 and 146, SEQ ID NOS: 147 and 148 and SEQ ID NOS: 153 and 154. Se proporciona un ácido ribonucleico bicatenario que comprende una combinación de hebra codificante y hebra no codificante, en donde la combinación de la hebra codificante y la hebra no codificante se selecciona entre el grupo que consiste en las combinaciones: SEC. ID NO: 159 y 160, SEC. ID NO: 141 y 142, SEC. ID NO: 143 y 144, SEC. ID NO: 145 y 146, SEC. ID NO: 147 y 148 y SEC. ID NO: 153 y 154.