KRAS G12C INHIBITORS AND METHODS OF USING THE SAME

Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers. En el presente documento se proporcionan inhibidores de KRAS G12C, una composición de...

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Hauptverfasser:	WURZ Ryan Paul, CEE Victor J, SHIN Youngsook, NISHIMURA Nobuko, PICKRELL Alexander J, TAMAYO Nuria A, XUE Qiufen, LIU Longbin, SIEGMUND Aaron C, WANG Hui-ling, REED Anthony B, MINATTI Ana Elena, GOODMAN Clifford, MA Vu Van, AMEGADZIE Albert, LANMAN Brian Alan, FROHN Michael J, KOPECKY David John, WALTON Mary, ALLEN John Gordon, LOPEZ Patricia, LOW Jonathan D, BOOKER Shon, CHEN Ning, TEGLEY Christopher M, NGUYEN Thomas T, CHEN Jian Jeffrey, ALLEN Jennifer Rebecca
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers. En el presente documento se proporcionan inhibidores de KRAS G12C, una composición de los mismos y métodos de uso de los mismos. Dichos inhibidores son útiles para el tratamiento de múltiples trastornos, incluyendo cáncer pancreático, colorrectal y de pulmón.