METHOD FOR PRODUCING 5-HYDROXYALKYL-SUBSTITUTED 1-PHENYL-1,2,4- TRIAZOLE DERIVATIVES

The invention relates to a novel and improved method for producing 5-(hydroxyalkyl)-1-phenyl-1,2,4-triazole-derivatives of the formula (I), in which R1A and R1B are selected independently of each other from the group comprising hydrogen, fluorine, chlorine, methyl, monofluoromethyl, difluoromethyl, trifluoromethyl, methoxy, difluoromethoxy, and trifluoromethoxy, to novel precursors for the production, and to the production and to the use of the crystalline modification I of (5-(4-chlorophenyl)-2-({ 1-(3-chlorophenyl)-5-[(1S)-1-hydroxyethyl]-1H-1,2 ,4-triazole-3-yl}methyl)- 4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3 H -1,2,4-triazole-3-one. La presente solicitud se refiere a un procedimiento novedoso y mejorado para la preparación de derivados de 5-(hidroxialquilo)-1- fenilo-1,2,4-triazol de la fórmula (I) (ver Fórmula) en la que R1A y R1B se seleccionan independientemente del grupo que consiste en hidrógeno, flúor, cloro, metilo, monofluormetilo, difluormetilo, trifluormetilo, etilo, metoxi, difluormetoxi y trifluormetoxi, nuevas fases previas para su preparación y la preparación y el uso de la modificación cristalina I de (5-(4-clorofenil)-2-({1-(3-clorofenil)-5-[(1S)-1-hidroxietil]-1H- 1,2,4-triazol-3-ilo}metilo)-4-[(2S)-3,3,3-trifluor-2-hidroxipropi l]-2,4-dihidro-3H-1,2,4-triazol-3-ona de la fórmula (I-A-1).