SOLID FORMS OF A PLASMA KALLIKREIN INHIBITOR AND SALTS THEREOF

SOLID FORMS OF A PLASMA KALLIKREIN INHIBITOR AND SALTS THEREOF

New solid forms of the plasma kallikrein inhibitor, 1‐({4‐[(5‐fluoro‐2‐oxopyridin‐1‐ yl)methyl]phenyl}methyl)‐N‐[(3‐fluoro‐4‐methoxypyridi n‐2‐yl)methyl]‐3‐(methoxymethyl)pyrazole‐4‐ carboxamide and its salts, are described. Se describen nuevas formas sólidas del...

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Hauptverfasser: SHARP Emma Kay, CROWE David Malcolm, LELIEVELD Ruben Henricus Carolus Adrianus Titus, TODD Richard Simon, MACDONALD-BROWN Stephen Mark, ARET Edwin, GHANDI Kiran
Format: Patent
Sprache:eng ; spa
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:New solid forms of the plasma kallikrein inhibitor, 1‐({4‐[(5‐fluoro‐2‐oxopyridin‐1‐ yl)methyl]phenyl}methyl)‐N‐[(3‐fluoro‐4‐methoxypyridi n‐2‐yl)methyl]‐3‐(methoxymethyl)pyrazole‐4‐ carboxamide and its salts, are described. Se describen nuevas formas sólidas del inhibidor de la calicreína en plasma, 1-({4-[(5-fluoro-2- oxopiridin-1-il) metil]fenil}metil)-N-[(3-fluoro-4-metoxipiridina-2-il)metil]-3-(m etoximetil)pirazol-4- carboxamida y sus sales.