METHODS, COMPOSITIONS, AND IMPLANTABLE ELEMENTS COMPRISING ACTIVE CELLS

Described herein are cell compositions comprising an active cell (e.g., an engineered active cell, e.g., an engineered RPE cell) or derivatives thereof, as well as compositions, pharmaceutical products, and implantable elements comprising an active cell, and methods of making and using the same. The...

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Bibliographische Detailangaben
Hauptverfasser:	HEIDEBRECHT Richard, OBERLI Matthias Alexander, CARMONA Guillaume, PERITT David, SEWELL Jered, A, VEISEH Omid, WOTTON Paul Kevin, SMITH Devyn Mckinley, MILLER Robert James, GONZALEZ Francisco Caballerro
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Described herein are cell compositions comprising an active cell (e.g., an engineered active cell, e.g., an engineered RPE cell) or derivatives thereof, as well as compositions, pharmaceutical products, and implantable elements comprising an active cell, and methods of making and using the same. The cells and compositions may express a therapeutic agent useful for the treatment of a disease, disorder, or condition described herein. En el presente documento se describen composiciones celulares que comprenden una célula activa (por ejemplo, una célula activa modificada por ingeniería genética, por ejemplo, una célula RPE modificada por ingeniería genética), o derivados de las mismas, así como composiciones, productos farmacéuticos y elementos implantables que comprenden una célula activa, y métodos para fabricar y usar la misma. Las células y las composiciones pueden expresar un agente terapéutico útil para el tratamiento de una enfermedad, trastorno o afección descrita en el presente documento.