IMMUNOGENIC COMPOSITIONS COMPRISING STAPHYLOCOCCUS AUREUS LEUKOCIDIN LUKA AND LUKB DERIVED POLYPEPTIDES

The present disclosure provides immunogenic compositions useful in prevention and treatment of Staphylococcus aureus infection. In particular, the disclosure provides methods of inducing an immune response against a LukAB-expressing S. aureus, methods of preventing or treating S. aureus infections,...

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Bibliographische Detailangaben
Hauptverfasser:	KORT Thomas, KAILASAN Shweta, AMAN Mohammad Javad, WILLISTON Nils, KARAUZUM Hatice, ADHIKARI Rajan P
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present disclosure provides immunogenic compositions useful in prevention and treatment of Staphylococcus aureus infection. In particular, the disclosure provides methods of inducing an immune response against a LukAB-expressing S. aureus, methods of preventing or treating S. aureus infections, and composition for preventing or treating S. aureus infections. La presente descripción proporciona composiciones inmunogénicas útiles en la prevención y el tratamiento de infecciones por Staphylococcus aureus. En particular, la descripción proporciona métodos para inducir una respuesta inmunitaria contra un S. aureus que expresa LukAB, métodos para prevenir o tratar infecciones por S. aureus y una composición para prevenir o tratar infecciones por S. aureus.