THERAPEUTIC ANTIBODIES BASED ON MUTATED IGG HEXAMERS
The present invention relates to formulation of antibodies. The invention relates in particular to pharmaceutical compositions comprising an antibody molecule of the IgG1 isotype having a mutation in the Fc region that enhances clustering of IgG molecules after cell-surface antigen binding. La prese...
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| creator | Andrew HAGARMAN Mette Hamborg JENSEN Cale HALBLEIB Lene Schantz HARLOW |
| description | The present invention relates to formulation of antibodies. The invention relates in particular to pharmaceutical compositions comprising an antibody molecule of the IgG1 isotype having a mutation in the Fc region that enhances clustering of IgG molecules after cell-surface antigen binding.
La presente invención se refiere a una formulación de anticuerpos. La invención se refiere en particular a composiciones farmacéuticas que comprenden una molécula de anticuerpo del isotipo IgG1 que tiene una mutación en la región Fc que mejora el agrupamiento de moléculas IgG después de la unión a antígeno de superficie celular. |
| format | Patent |
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La presente invención se refiere a una formulación de anticuerpos. La invención se refiere en particular a composiciones farmacéuticas que comprenden una molécula de anticuerpo del isotipo IgG1 que tiene una mutación en la región Fc que mejora el agrupamiento de moléculas IgG después de la unión a antígeno de superficie celular.</description><language>eng ; spa</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200205&DB=EPODOC&CC=MX&NR=2019014407A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200205&DB=EPODOC&CC=MX&NR=2019014407A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Andrew HAGARMAN</creatorcontrib><creatorcontrib>Mette Hamborg JENSEN</creatorcontrib><creatorcontrib>Cale HALBLEIB</creatorcontrib><creatorcontrib>Lene Schantz HARLOW</creatorcontrib><title>THERAPEUTIC ANTIBODIES BASED ON MUTATED IGG HEXAMERS</title><description>The present invention relates to formulation of antibodies. The invention relates in particular to pharmaceutical compositions comprising an antibody molecule of the IgG1 isotype having a mutation in the Fc region that enhances clustering of IgG molecules after cell-surface antigen binding.
La presente invención se refiere a una formulación de anticuerpos. La invención se refiere en particular a composiciones farmacéuticas que comprenden una molécula de anticuerpo del isotipo IgG1 que tiene una mutación en la región Fc que mejora el agrupamiento de moléculas IgG después de la unión a antígeno de superficie celular.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAJ8XANcgxwDQ3xdFZw9AvxdPJ38XQNVnByDHZ1UfD3U_ANDXEMATI93d0VPFwjHH1dg4J5GFjTEnOKU3mhNDeDkptriLOHbmpBfnxqcUFicmpeakm8b4SRgaGlgaGJiYG5ozFRigAL3ifB</recordid><startdate>20200205</startdate><enddate>20200205</enddate><creator>Andrew HAGARMAN</creator><creator>Mette Hamborg JENSEN</creator><creator>Cale HALBLEIB</creator><creator>Lene Schantz HARLOW</creator><scope>EVB</scope></search><sort><creationdate>20200205</creationdate><title>THERAPEUTIC ANTIBODIES BASED ON MUTATED IGG HEXAMERS</title><author>Andrew HAGARMAN ; Mette Hamborg JENSEN ; Cale HALBLEIB ; Lene Schantz HARLOW</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MX2019014407A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>Andrew HAGARMAN</creatorcontrib><creatorcontrib>Mette Hamborg JENSEN</creatorcontrib><creatorcontrib>Cale HALBLEIB</creatorcontrib><creatorcontrib>Lene Schantz HARLOW</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Andrew HAGARMAN</au><au>Mette Hamborg JENSEN</au><au>Cale HALBLEIB</au><au>Lene Schantz HARLOW</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>THERAPEUTIC ANTIBODIES BASED ON MUTATED IGG HEXAMERS</title><date>2020-02-05</date><risdate>2020</risdate><abstract>The present invention relates to formulation of antibodies. The invention relates in particular to pharmaceutical compositions comprising an antibody molecule of the IgG1 isotype having a mutation in the Fc region that enhances clustering of IgG molecules after cell-surface antigen binding.
La presente invención se refiere a una formulación de anticuerpos. La invención se refiere en particular a composiciones farmacéuticas que comprenden una molécula de anticuerpo del isotipo IgG1 que tiene una mutación en la región Fc que mejora el agrupamiento de moléculas IgG después de la unión a antígeno de superficie celular.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | THERAPEUTIC ANTIBODIES BASED ON MUTATED IGG HEXAMERS |
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