METHODS AND MICROORGANISMS FOR MAKING 2,3-BUTANEDIOL AND DERIVATIVES THEREOF FROM C1 CARBONS

Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 2,3-BDO are disclosed. For example, genetically modified methanotrophs that are capable of generating 2,3-BDO at high titers from a methane source are disclosed. Methods of making th...

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Bibliographische Detailangaben
Hauptverfasser: Xinhua ZHAO, Na TRINH, Lily Yuin CHAO, James KEALEY, Mark Anton HELD, Tina HUYNH, Matthias Helmut SCHAMLISCH, Kevin Lee DIETZEL, Bryan YEH
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 2,3-BDO are disclosed. For example, genetically modified methanotrophs that are capable of generating 2,3-BDO at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed. La presente invención se refiere a microorganismos genéticamente modificados que tienen la capacidad para convertir sustratos de carbono en productos químicos tales como 2,3-BDO. Por ejemplo, se describen metanotrofos genéticamente modificados que son capaces de generar 2,3-BDO a tituladores elevados a partir de una fuente de metano. También se describen estos microorganismos genéticamente modificados y métodos para usarlos.