PORCINE CORONAVIRUS VACCINES

The present invention relates to a vaccine for protecting a pig against diseases associated with corona virus infection including porcine epidemic diarrhea virus (PEDV) and/or porcine deltacorona virus (PDCoV). The vaccine commonly includes inactivated/killed PEDV (e.g., chemically inactivated PED v...

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Hauptverfasser: Sean O''CONNER, Joseph Gilbert VICTORIA, Luis Alejandro HERNANDEZ, Abby Rae PATTERSON, Joseph Ralph HERMANN, Lea Ann HOBBS, Arun V. IYER, Eric Martin VAUGHN, Scott ACKERMAN
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The present invention relates to a vaccine for protecting a pig against diseases associated with corona virus infection including porcine epidemic diarrhea virus (PEDV) and/or porcine deltacorona virus (PDCoV). The vaccine commonly includes inactivated/killed PEDV (e.g., chemically inactivated PED virus), and/or recombinant PEDV antigen, and/or an adjuvant inactivated/killed PDCoV (e.g., chemically inactivated PDCoV virus), and/or recombinant PDCoV antigen and an adjuvant. Methods for protecting pigs against diseases associated with PEDV and/or PDCoV and methods of producing the porcine epidemic diarrhea virus and/or porcine deltacorona virus vaccine are also provided. La presente invención se refiere a una vacuna para proteger un cerdo contra enfermedades asociadas a la infección por coronavirus, que incluye el virus de la diarrea epidémica porcina (PEDV) y/o el deltacoronavirus porcino (PDCoV). La vacuna incluye comúnmente PEDV inactivado/suprimido (por ejemplo, virus de PED químicamente inactivado) y/o antígeno de PEDV recombinante, y/o un PDCoV inactivado/suprimido adyuvante (por ejemplo, virus PDCoV químicamente inactivado), y/o antígeno de PDCoV recombinante y un adyuvante. También se proporcionan métodos para proteger cerdos contra enfermedades asociadas a PEDV y/o PDCoV y metodos para producir la vacuna contra el virus de la diarrea epidémica porcina y/o el deltacoronavirus porcino.