COMBINATIONS OF FGFR4 INHIBITORS AND BILE ACID SEQUESTRANTS

The present invention relates to a pharmaceutical combination comprising an FGFR4 inhibitor and a bile acid sequestrant, to the use of the pharmaceutical combination in the treatment of cancer, to the use of a bile acid sequestrant to reduce or mitigate side-effects associated with FGFR4 inhibition...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Andreas WEISS, Kuno WUERSCH, Diana GRAUS PORTA, Robin Alec FAIRHURST, Jacqueline KINYAMU-AKUNDA, Luigi MANENTI, Andreas Joerg MAHL, Armin WOLF
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The present invention relates to a pharmaceutical combination comprising an FGFR4 inhibitor and a bile acid sequestrant, to the use of the pharmaceutical combination in the treatment of cancer, to the use of a bile acid sequestrant to reduce or mitigate side-effects associated with FGFR4 inhibition therapy. La presente invención se refiere a una combinación farmacéutica que comprende un inhibidor de FGFR4 y un secuestrante de ácido biliar, al uso de la combinación farmacéutica en el tratamiento de cáncer, y al uso de un secuestrante de ácido biliar con el fin de reducir o mitigar los efectos secundarios asociados con la terapia de inhibición de FGFR4.