DEPOT FORMULATIONS

Pharmaceutical compositions comprising an active pharmaceutical ingredient, a high viscosity liquid carrier material, a hydrophobic solvent, and a hydrophilic solvent are disclosed. Also disclosed are methods of manufacturing and using the compositions. The compositions are suitable for use, e.g., a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Komei OKABE, Wilma TAMRAZ, Weiqi LIN, Huey- Ching Lin SU, Kazuhito YAMADA, Naoki MATSUMOTO, Sreenivasu MUDUMBA
Format: Patent
Sprache:eng ; spa
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Beschreibung
Zusammenfassung:Pharmaceutical compositions comprising an active pharmaceutical ingredient, a high viscosity liquid carrier material, a hydrophobic solvent, and a hydrophilic solvent are disclosed. Also disclosed are methods of manufacturing and using the compositions. The compositions are suitable for use, e.g., as depot formulations. Se describen composiciones farmacéuticas que comprenden un ingrediente farmacéutico activo, un material portador líquido de alta viscosidad, un solvente hidrófobo y un solvente hidrófilo. También se describen métodos de fabricación y de uso de las composiciones. Las composiciones son adecuadas para su uso, por ejemplo, como formulaciones de depósito.