ANTI-ROR1 ANTIBODIES, ROR1 X CD3 BISPECIFIC ANTIBODIES, AND METHODS OF USING THE SAME

Provided herein are isolated antibodies that immunospecifically bind to ROR1, bispecific antibodies comprising an antigen-binding site that immunospecifically binds to ROR1 and an antigen-binding site that immunospecifically binds to CD3, and methods of using the same. En la presente descripcion se...

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Bibliographische Detailangaben
Hauptverfasser:	Alexey TEPLYAKOV, Francois GAUDET, Glenn Mark ANDERSON, Eric T. BALDWIN, Susan H. TAM, Sheng- Jiun WU, Yingzhe LI, Ronan MCDAID, Rosa M. F. CARDOSO, Benjamin HARMAN, Steven C. POMERANTZ, Jinquan LUO, Jennifer F. NEMETH-SEAY, Ricardo ATTAR
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Provided herein are isolated antibodies that immunospecifically bind to ROR1, bispecific antibodies comprising an antigen-binding site that immunospecifically binds to ROR1 and an antigen-binding site that immunospecifically binds to CD3, and methods of using the same. En la presente descripcion se proporcionan anticuerpos aislados que se unen inmunoespecificamente a ROR1, anticuerpos biespecificos que comprenden un sitio de union al antigeno que se une inmunoespecificamente a ROR1 y un sitio de union al antigeno que se une inmunoespecificamente a CD3, y metodos para su uso.