PHARMACEUTICAL COMPOSITE PREPARATION

The present invention relates to a tablet which contains, as active ingredients, candesartan or candesartan cilexetil and amlodipine or a pharmaceutically acceptable salt thereof, and which uses a specific solubilizing agent in order to significantly improve the stability and elution of the active i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Woo- Ile PARK, Ah- Reum CHAE, Jae-Young Lee, Woo- Kyung KIM, Jei- Man RYU, Hyun- Woo JUNG, Kyoung- Hwan KANG, Soo- Won KIM
Format: Patent
Sprache:eng ; spa
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Beschreibung
Zusammenfassung:The present invention relates to a tablet which contains, as active ingredients, candesartan or candesartan cilexetil and amlodipine or a pharmaceutically acceptable salt thereof, and which uses a specific solubilizing agent in order to significantly improve the stability and elution of the active ingredient. In addition, the present invention relates to a method for preparing the tablet. La presente invención se relaciona con una tableta que comprende candesartán o candesartán cilexetilo y amlodipina o su sal farmacéuticamente aceptable como ingredientes activos, la tableta utiliza un solubilizante particular para mejorar significativamente las propiedades de estabilidad y disolución de los ingredientes activos. Además, la presente invención se relaciona con un método para preparar la tableta.