INHIBITORS OF THE MENIN-MLL INTERACTION

The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction. La presente invención se dirige a inhibido...

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Hauptverfasser: ZANG, Linghang, Chengguo DONG, CLAREMON, David A, VENKATRAMAN, Shankar, Suresh B. SINGH, Lanqi JIA, Yi FAN, ZHENG, Yajun, YUAN, Jing
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creator ZANG, Linghang
Chengguo DONG
CLAREMON, David A
VENKATRAMAN, Shankar
Suresh B. SINGH
Lanqi JIA
Yi FAN
ZHENG, Yajun
YUAN, Jing
description The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction. La presente invención se dirige a inhibidores de la interacción de menina con MLL y proteínas de fusión de MLL, composiciones farmacéuticas que contienen los mismos, y su uso en el tratamiento de cáncer y otras enfermedades mediante por la interacción de menina-MML.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title INHIBITORS OF THE MENIN-MLL INTERACTION
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