FORMULATION OF L-ORNITHINE PHENYLACETATE
Some embodiments of the present application are directed to oral formulations of L- ornithine phenylacetate and methods of using the same. These oral formulations offer alternative administration route than the standard intravenous administration of L-ornithine phenylacetate for treating hyperammone...
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Zusammenfassung: | Some embodiments of the present application are directed to oral formulations of L- ornithine phenylacetate and methods of using the same. These oral formulations offer alternative administration route than the standard intravenous administration of L-ornithine phenylacetate for treating hyperammonemia in patients having various acute and chronic liver diseases and disorders, for example, acute liver failure, liver cirrhosis, liver decompensation, portal hypertension, hepatic encephalopathy, or patients with urea cycle disorders.
Algunas modalidades de la presente solicitud se refieren a formulaciones orales de fenilacetato de L-ornitina y métodos para usar las mismas. Estas formulaciones orales ofrecen ruta alternativa de administración que la administración intravenosa estándar de fenilacetato de Lornitina para tratar hiperamonemia en pacientes que tienen enfermedades y trastornos agudos y crónicos del hígado, por ejemplo, falla hepática aguda, descompensación hepática, hipertensión portal, encefalopatía hepática, o pacientes con trastornos del ciclo de urea. |
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