PYRAZINE DERIVATIVES AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS

The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform. La presente invención proporciona los compuestos de la fórmula (I): (ver Fórmula) l...

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Bibliographische Detailangaben
Hauptverfasser:	Ian BRUCE, Matthew SPENDIFF, Andrew James CULSHAW, Benjamin Richard BELLENIE, James NEEF, Gregory HOLLINGWORTH, Simon James WATSON
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides compounds of formula (I) which inhibit the activity of PI 3-kinase gamma isoform, which are useful for the treatment of diseases mediated by the activation of PI 3-kinase gamma isoform. La presente invención proporciona los compuestos de la fórmula (I): (ver Fórmula) los cuales inhiben la actividad de la isoforma gamma de Pl3-cinasa, y los cuales son útiles para el tratamiento de las enfermedades mediadas por la activación de la isoforma gamma de PI3-cinasa.