METHODS AND PHARMACEUTICAL COMPOSITIONS FOR EXPRESSING A POLYNUCLEOTIDE OF INTEREST IN THE RETINAL PIGMENT EPITHELIUM OF A SUBJECT

The present invention relates to methods and pharmaceutical compositions for expressing a polynucleotide of interest in the retinal pigment epithelium of a subject. In particular, the present invention relates to a method for selectively expressing a polynucleotide of interest in the retinal pigment...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Nicolas CERESO, Christian HAMEL, Vasiliki KALATZIS, Marie PEQUIGNOT
Format: Patent
Sprache:eng ; spa
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Nicolas CERESO
Christian HAMEL
Vasiliki KALATZIS
Marie PEQUIGNOT
description The present invention relates to methods and pharmaceutical compositions for expressing a polynucleotide of interest in the retinal pigment epithelium of a subject. In particular, the present invention relates to a method for selectively expressing a polynucleotide of interest in the retinal pigment epithelium in an eye of a subject in need thereof comprising the step of transducing the retinal pigment epithelium with an amount of a rAAV2/5 vector containing the polynucleotide of interest. La presente invención se refiere a métodos y a composiciones farmacéuticas para la expresión de un polinucleótido de interés en el epitelio pigmentario retiniano de un sujeto. En particular, la presente invención se refiere a un método para expresar selectivamente un polinucleótido de interés en el epitelio pigmentario retiniano en un ojo de un sujeto con necesidad del mismo que comprende la etapa de transducir el epitelio pigmentario retiniano con una cantidad de un vector rAAV2/5 que contiene el polinucleótido de interés.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_MX2016007278A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>MX2016007278A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_MX2016007278A3</originalsourceid><addsrcrecordid>eNqNjEsKwkAQRLNxIeodGvdCjKBux0kn0zI_ZjoQVyHIuBINxBN4ciN4AFdV1HvUPHsbZOXKCMKW4JUIRkhsmKTQIJ3xLhKTsxEqFwBbHzBGsjUI8E5fbCM1OqYSwVVAlnHiPBVghRCQyU4_nmqDlgE9TbOmxnxtAbE5nVHyMpvd-vuYVr9cZOsKWapNGp5dGof-mh7p1Zm2yLf7PD8Uh6PY_SV9AJjrPYA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>METHODS AND PHARMACEUTICAL COMPOSITIONS FOR EXPRESSING A POLYNUCLEOTIDE OF INTEREST IN THE RETINAL PIGMENT EPITHELIUM OF A SUBJECT</title><source>esp@cenet</source><creator>Nicolas CERESO ; Christian HAMEL ; Vasiliki KALATZIS ; Marie PEQUIGNOT</creator><creatorcontrib>Nicolas CERESO ; Christian HAMEL ; Vasiliki KALATZIS ; Marie PEQUIGNOT</creatorcontrib><description>The present invention relates to methods and pharmaceutical compositions for expressing a polynucleotide of interest in the retinal pigment epithelium of a subject. In particular, the present invention relates to a method for selectively expressing a polynucleotide of interest in the retinal pigment epithelium in an eye of a subject in need thereof comprising the step of transducing the retinal pigment epithelium with an amount of a rAAV2/5 vector containing the polynucleotide of interest. La presente invención se refiere a métodos y a composiciones farmacéuticas para la expresión de un polinucleótido de interés en el epitelio pigmentario retiniano de un sujeto. En particular, la presente invención se refiere a un método para expresar selectivamente un polinucleótido de interés en el epitelio pigmentario retiniano en un ojo de un sujeto con necesidad del mismo que comprende la etapa de transducir el epitelio pigmentario retiniano con una cantidad de un vector rAAV2/5 que contiene el polinucleótido de interés.</description><language>eng ; spa</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20160916&amp;DB=EPODOC&amp;CC=MX&amp;NR=2016007278A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20160916&amp;DB=EPODOC&amp;CC=MX&amp;NR=2016007278A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Nicolas CERESO</creatorcontrib><creatorcontrib>Christian HAMEL</creatorcontrib><creatorcontrib>Vasiliki KALATZIS</creatorcontrib><creatorcontrib>Marie PEQUIGNOT</creatorcontrib><title>METHODS AND PHARMACEUTICAL COMPOSITIONS FOR EXPRESSING A POLYNUCLEOTIDE OF INTEREST IN THE RETINAL PIGMENT EPITHELIUM OF A SUBJECT</title><description>The present invention relates to methods and pharmaceutical compositions for expressing a polynucleotide of interest in the retinal pigment epithelium of a subject. In particular, the present invention relates to a method for selectively expressing a polynucleotide of interest in the retinal pigment epithelium in an eye of a subject in need thereof comprising the step of transducing the retinal pigment epithelium with an amount of a rAAV2/5 vector containing the polynucleotide of interest. La presente invención se refiere a métodos y a composiciones farmacéuticas para la expresión de un polinucleótido de interés en el epitelio pigmentario retiniano de un sujeto. En particular, la presente invención se refiere a un método para expresar selectivamente un polinucleótido de interés en el epitelio pigmentario retiniano en un ojo de un sujeto con necesidad del mismo que comprende la etapa de transducir el epitelio pigmentario retiniano con una cantidad de un vector rAAV2/5 que contiene el polinucleótido de interés.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjEsKwkAQRLNxIeodGvdCjKBux0kn0zI_ZjoQVyHIuBINxBN4ciN4AFdV1HvUPHsbZOXKCMKW4JUIRkhsmKTQIJ3xLhKTsxEqFwBbHzBGsjUI8E5fbCM1OqYSwVVAlnHiPBVghRCQyU4_nmqDlgE9TbOmxnxtAbE5nVHyMpvd-vuYVr9cZOsKWapNGp5dGof-mh7p1Zm2yLf7PD8Uh6PY_SV9AJjrPYA</recordid><startdate>20160916</startdate><enddate>20160916</enddate><creator>Nicolas CERESO</creator><creator>Christian HAMEL</creator><creator>Vasiliki KALATZIS</creator><creator>Marie PEQUIGNOT</creator><scope>EVB</scope></search><sort><creationdate>20160916</creationdate><title>METHODS AND PHARMACEUTICAL COMPOSITIONS FOR EXPRESSING A POLYNUCLEOTIDE OF INTEREST IN THE RETINAL PIGMENT EPITHELIUM OF A SUBJECT</title><author>Nicolas CERESO ; Christian HAMEL ; Vasiliki KALATZIS ; Marie PEQUIGNOT</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MX2016007278A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2016</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>Nicolas CERESO</creatorcontrib><creatorcontrib>Christian HAMEL</creatorcontrib><creatorcontrib>Vasiliki KALATZIS</creatorcontrib><creatorcontrib>Marie PEQUIGNOT</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Nicolas CERESO</au><au>Christian HAMEL</au><au>Vasiliki KALATZIS</au><au>Marie PEQUIGNOT</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHODS AND PHARMACEUTICAL COMPOSITIONS FOR EXPRESSING A POLYNUCLEOTIDE OF INTEREST IN THE RETINAL PIGMENT EPITHELIUM OF A SUBJECT</title><date>2016-09-16</date><risdate>2016</risdate><abstract>The present invention relates to methods and pharmaceutical compositions for expressing a polynucleotide of interest in the retinal pigment epithelium of a subject. In particular, the present invention relates to a method for selectively expressing a polynucleotide of interest in the retinal pigment epithelium in an eye of a subject in need thereof comprising the step of transducing the retinal pigment epithelium with an amount of a rAAV2/5 vector containing the polynucleotide of interest. La presente invención se refiere a métodos y a composiciones farmacéuticas para la expresión de un polinucleótido de interés en el epitelio pigmentario retiniano de un sujeto. En particular, la presente invención se refiere a un método para expresar selectivamente un polinucleótido de interés en el epitelio pigmentario retiniano en un ojo de un sujeto con necesidad del mismo que comprende la etapa de transducir el epitelio pigmentario retiniano con una cantidad de un vector rAAV2/5 que contiene el polinucleótido de interés.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; spa
recordid cdi_epo_espacenet_MX2016007278A
source esp@cenet
subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title METHODS AND PHARMACEUTICAL COMPOSITIONS FOR EXPRESSING A POLYNUCLEOTIDE OF INTEREST IN THE RETINAL PIGMENT EPITHELIUM OF A SUBJECT
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T08%3A30%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Nicolas%20CERESO&rft.date=2016-09-16&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EMX2016007278A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true