DIPHENYLOX

The present invention relates to diphenyloxyalkylamine derivatives and aryloxyalkylamine derivatives that are structurally analogous to mexiletine, said derivatives having important biological activity and not causing the undesired side effects observed with the prototype, as well as with other drug...

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Hauptverfasser: Marcus Vinicius Nora DE SOUZA, Robson Xavier FARIA, Magda Fraguas SERRA, Emerson Teixeira DA SILVA, Jorge Carlos Santos DA COSTA, Marco Aurélio MARTINS
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creator Marcus Vinicius Nora DE SOUZA
Robson Xavier FARIA
Magda Fraguas SERRA
Emerson Teixeira DA SILVA
Jorge Carlos Santos DA COSTA
Marco Aurélio MARTINS
description The present invention relates to diphenyloxyalkylamine derivatives and aryloxyalkylamine derivatives that are structurally analogous to mexiletine, said derivatives having important biological activity and not causing the undesired side effects observed with the prototype, as well as with other drugs from the same therapeutic class as the prototype. The derivatives of the present invention have formulas II and III and are used for treating, preventing or inhibiting pulmonary inflammatory diseases, for example, asthma and chronic obstructive pulmonary disease (COPD). La presente invención se refiere a derivados de difeniloxialquilamina y derivados de ariloxialquilamina que son estructuralmente análogos a mexiletina, dichos derivados con actividad biológica importante y sin causar efectos secundarios no deseados observados con el prototipo, así como con otros fármacos de la misma clase terapéutica que el prototipo; los derivados de la presente invención tienen fórmulas II y III y se utilizan para tratar, prevenir o inhibir enfermedades inflamatorias pulmonares, por ejemplo, asma y enfermedad pulmonar obstructiva crónica (COPD).
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The derivatives of the present invention have formulas II and III and are used for treating, preventing or inhibiting pulmonary inflammatory diseases, for example, asthma and chronic obstructive pulmonary disease (COPD). 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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title DIPHENYLOX
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