AMINOMETHYL-BIARYL DERIVATIVES AS COMPLEMENT FACTOR D INHIBITORS AND USES THEREOF

The present invention provides a compound of formula (I), a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. La presente invención proporciona u...

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Hauptverfasser: OLIVIER ROGEL, STEFANIE FLOHR, DONGLEI LIU, JAMES J. POWERS, NAN JI, CHRISTINE FANG GELIN, ANNA VULPETTI, STEFAN ANDREAS RANDL, KEITH JENDZA, RAJESHRI GANESH KARKI, NELLO MAINOLFI, TAEYOUNG YOON, DAVID B. BELANGER, EDWIGE LILIANE JEANNE LORTHIOIS
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The present invention provides a compound of formula (I), a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. La presente invención proporciona un compuesto de la fórmula I: (ver Fórmula) un método para la elaboración de los compuestos de la invención, y sus usos terapéuticos. La presente invención proporciona además una combinación de agentes farmacológicamente activos y una composición farmacéutica.