FUSED PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS

FUSED PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS

The invention relates to fused piperidine amides useful as inhibitors of ion channels for the treatment of pain. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SARA SABINA HADIDA-RUAH, FABRICE JEAN DENIS PIERRE, MICHAEL PAUL DENINNO, PETER DIEDERIK JAN GROOTENHUIS, ERICA LYNN CONROY, JOHNNY UY, COREY ANDERSON, DENNIS JAMES HURLEY, ALINA SILINA, JINGLAN ZHOU, BRYAN A. FRIEMAN
Format: Patent
Sprache:eng ; spa
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention relates to fused piperidine amides useful as inhibitors of ion channels for the treatment of pain. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. La invención se refiere a amidas de piperidina fusionadas útiles como inhibidores de los canales de iones para el tratamiento de dolor. La invención también proporciona composiciones farmacéuticamente aceptables que comprenden los compuestos de la invención y métodos para usar las composiciones en el tratamiento de varios trastornos.