NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF CYSTIC FIBROSIS

The present invention discloses compounds according to Formula (I), wherein R1, R2, R3, L, and the subscript m are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions, and methods o...

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Bibliographische Detailangaben
Hauptverfasser:	CHRISTEL MENET, CAROLINE JOANESSE, GIOVANNI TRICARICO, ANN DE BLIECK, HANS KELGTERMANS, OSCAR MAMMOLITI, STEVEN VAN DER PLAS, TOM DE MUNCK
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention discloses compounds according to Formula (I), wherein R1, R2, R3, L, and the subscript m are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions, and methods of treatment using the same, for the treatment of cystic fibrosis by administering a compound of the invention. La presente invención describe compuestos de acuerdo a la Fórmula I: (ver Fórmula) en donde R1, R2, R3, L, y el subíndice m son como se definió en la presente. La presente invención se refiere a compuestos y su uso en el tratamiento de fibrosis quística, métodos para su producción, composiciones farmacéuticas, y métodos de tratamiento usando el mismo, para el tratamiento de fibrosis quística al administrar un compuesto de la invención.