PYRAZOLO COMPOUNDS AND USES THEREOF

Provided are compounds useful as inhibitors of one or more histone demethylses, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using the present composition in the treatment of various disorders. Se prop...

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Bibliographische Detailangaben
Hauptverfasser:	KWONG WAH LAI, JUN LIANG, STEVEN F. BELLON, DAN ORTWINE, SHARADA LABADIE, VICTOR S. GEHLING, BRIAN K. ALBRECHT, JEANRISTOPHE HARMANGE, BIRONG ZHANG, PETER DRAGOVICH
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided are compounds useful as inhibitors of one or more histone demethylses, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using the present composition in the treatment of various disorders. Se proporcionan compuestos útiles como inhibidores de una o más demetilasas de histona, tales como KDM5. La invención igualmente proporciona composiciones farmacéuticamente aceptables que comprenden los compuestos de la presente invención y los métodos para usar la presente composición en el tratamiento de diversos trastornos.