COMPOSITIONS AND METHODS FOR THE TREATMENT OF ECTODERMAL DYSPLASIA

The invention relates to pharmaceutical compositions and methods for the treatment of ectodermal displasias via the administration of EDA agonists, in particular EDI200. Use of the compositions and methods described allow for therapeutic dosing and administration regimens in human patients to correc...

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Bibliographische Detailangaben
Hauptverfasser: NEIL KIRBY, PASCAL SCHNEIDER, KENNETH M. HUTTNER, OLIVIER GAIDE
Format: Patent
Sprache:eng ; spa
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Beschreibung
Zusammenfassung:The invention relates to pharmaceutical compositions and methods for the treatment of ectodermal displasias via the administration of EDA agonists, in particular EDI200. Use of the compositions and methods described allow for therapeutic dosing and administration regimens in human patients to correct or alter abnormal phenotypes associated with genetic disorders, in particular, XLHED. La invención se relaciona con composiciones farmacéuticas y métodos para el tratamiento de displasias ectodérmicas vía la administración de agonistas EDA, en particular EDI200. El uso de las composiciones y métodos descritos permite regímenes de dosificación terapéutica y administración en pacientes humanos para corregir o altera fenotipos anormales asociados con trastornos genéticos, en particular, XLHED.