ENZYMATIC PRODUCTION OF CYTOSINIC NUCLEOSIDE ANALOGUES

The invention relates to the enzymatic production of cytosinic nucleoside analogues. In particular this invention is related to a new synthesis process of cytosine nucleoside analogues by using nucleoside phosphorylase enzymes, particularly Pyrimidin Nucleoside Phosphorylases (PyNPs) or mixtures of...

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Hauptverfasser: PASCUAL GILABERT, Marta, PASCUAL GILABERT M. Marta, DERONCELÉ THOMAS, Víctor M, MONTILLA ARÉVALO, Rafael
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The invention relates to the enzymatic production of cytosinic nucleoside analogues. In particular this invention is related to a new synthesis process of cytosine nucleoside analogues by using nucleoside phosphorylase enzymes, particularly Pyrimidin Nucleoside Phosphorylases (PyNPs) or mixtures of Purine Nucleoside Phosphorylases (PNPs) and PyNPs. Producción enzimática de análogos nucleosídicos de citosina La invención se refiere a un nuevo proceso de síntesis de análogos nucleosídicos de citosina usando enzimas nucleósido fosforilasa, particularmente pirimidina nucleósido fosforilasas (PyNP) o mezclas de purina nucleósido fosforilasas (PNP) y PyNP.