PARENTERAL FORMULATION OF RASAGILINE

This application provides a method of preferentially inhibiting monoamine oxidase A (MAOA) in the brain of a subject relative to in the intestine of the subject comprising parenterally administering to the subject a controlled release formulation comprising a therapeutically effective amount of rasa...

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Bibliographische Detailangaben
Hauptverfasser: ERAN BLAUGRUND, AVIVA GROSS, ROM E. ELIAZ, ADI MAYK, CHERYL FITZER-ATTAS
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:This application provides a method of preferentially inhibiting monoamine oxidase A (MAOA) in the brain of a subject relative to in the intestine of the subject comprising parenterally administering to the subject a controlled release formulation comprising a therapeutically effective amount of rasagiline or a pharmaceutically acceptable salt thereof. Esta solicitud proporciona un método para inhibir preferentemente oxidasa de monoamina A (MAOA) en el cerebro de un sujeto en relación con el intestino del sujeto, que comprende administrar parenteralmente al sujeto una formulación de liberación controlada que comprende una cantidad terapéuticamente efectiva de rasagilina o una sal farmacéuticamente aceptable del mismo.