SULFONAMIDE DERIVATIVE AND MEDICINAL USE THEREOF

Provided is a sulfonamide derivative of a specific chemical structure that has terminal sulfonamide groups having, as substituents, phenyl groups or heterocyclic groups with heteroatoms as constituent elements, or a pharmaceutically acceptable salt thereof. These compounds are novel compounds having...

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Hauptverfasser: TAROU NAKAMURA, SHUNSUKE KAGEYAMA, TAKASHI YAMAMOTO, TOMOKO MIYAZAWA, TOSHIHIKO SUGIURA, MIZUKI DOHI, RYUTA TAKASHITA, AYATOSHI ANDO, HIROKAZU UENO, AGUNG EVIRYANTI, MASAYUKI SUGIKI, HIROYUKI EDA, RYOHEI YOKOYAMA, AYA KIRIHARA, ITSUYA TANABE, MANAMI SHUTO, MISATO NOGUCHI
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:Provided is a sulfonamide derivative of a specific chemical structure that has terminal sulfonamide groups having, as substituents, phenyl groups or heterocyclic groups with heteroatoms as constituent elements, or a pharmaceutically acceptable salt thereof. These compounds are novel compounds having excellent α4-integrin-inhibiting activity. Se proporciona un derivado de sulfonamida de una estructura química específica que tiene grupos sulfonamida terminales, que tiene, como sustituyentes, grupos fenilo o grupos heterocíclicos con heteroátomos como elementos constituyentes, o una sal farmacéuticamente aceptable del mismo. Estos compuestos son compuestos novedosos que tienen excelente actividad de inhibición de a4-integrina.