4-1BB BINDING MOLECULES

The present disclosure provides isolated binding molecules that bind to human 4- BB, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceuti...

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Hauptverfasser: DUFIELD, ROBERT LEE, ZULLEY, MORITZ, ROHNER, ALLISON KARLYN, KAMPERSCHROER, CRIS, ONADIPE, ADEKUNLE OLATUNBOSUN, BAXI, SANGITA M, BERGQVIST, SIMON PAUL, JONES, HEATHER LAURENCE, LADETZKI-BAEHS, KATHRIN, FISHER, TIMOTHY SCOTT, SHARP, LESLIE LYNNE, THOMAS, KRISTIN ELIZABETH, YATES, LIBBEY ANNE, OLIPHANT, THEODORE LAWRENCE, AHRENS, BIANCA, JEROME, RICHARD MICHAEL, LOVE, VICTORIA ALEXANDRIA, RADHAKRISHNAN, VINAY, DOYONNAS, REGIS, ELLIOTT, MARK WILLIAM, ZIEGEMEIER, DAISY MARIE, TESAR, MICHAEL, QIN, WENNING
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The present disclosure provides isolated binding molecules that bind to human 4- BB, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions. La presente divulgación proporciona moléculas de unión aisladas que se unen a 4-1BB humano, moléculas de ácido nucleico que codifican una secuencia de aminoácidos de las moléculas de unión, vectores que comprenden las moléculas de ácido nucleico, células huésped que contienen los vectores, procedimientos para realizar las moléculas de unión, composiciones farmacéuticas que contienen las moléculas de unión y procedimientos para usar las moléculas de unión o composiciones.