CRYSTALLINE FORMS OF KINASE INHIBITORS

CRYSTALLINE FORMS OF KINASE INHIBITORS

Citrate salts of N-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2- c]pyridin-3-yl}phenyl)-N'-(3-fluorophenyl)urea and crystalline forms thereof are suitable pharmaceutical ingredients for pharmaceutical compositions useful in the treatment of disease, for example, cancer. Las sale...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JONATHAN MILLER, GEOFF G. Z. ZHANG, DOUG H. HOFFMAN
Format: Patent
Sprache:eng ; spa
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Citrate salts of N-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2- c]pyridin-3-yl}phenyl)-N'-(3-fluorophenyl)urea and crystalline forms thereof are suitable pharmaceutical ingredients for pharmaceutical compositions useful in the treatment of disease, for example, cancer. Las sales de citrato de N-(4-{4-amino-7-[1-(2-hidroxietil)-1H-pira zol-4-iI]tieno[3, 2-c]piridin-3-iI}fenil)N'-(3-fluorofenil)urea y las formas cristalinas de la misma, son ingredientes farmacéuticos adecuados para composiciones farmacéuticas útiles en el tratamiento de una enfermedad, por ejemplo, cáncer.