LIPOSOME OF IRINOTECAN OR ITS HYDROCHLORIDE AND PREPARATION METHOD THEREOF

A liposome of irinotecan or its hydrochloride and its preparation method are disclosed. The liposome comprises irinotecan or its hydrochloride, neutral phospholipid and cholesterol, wherein the weight ratio of cholesterol to neutral phospholipid is 1:3-5. Said liposome is prepared by ion gradient me...

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Bibliographische Detailangaben
Hauptverfasser: LIANGCHEN, XINYONG TONG, CHENGXIA YU, GUOFENG LEI
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:A liposome of irinotecan or its hydrochloride and its preparation method are disclosed. The liposome comprises irinotecan or its hydrochloride, neutral phospholipid and cholesterol, wherein the weight ratio of cholesterol to neutral phospholipid is 1:3-5. Said liposome is prepared by ion gradient method. Son descritos un liposoma de irinotecano o su clorhidrato y su método de preparación. El liposoma comprende irinotecano o su clorhidrato, fosfolípido neutro y colesterol, dando la relación en peso del colesterol al fosfolípido neutro es de 1:3-5. El liposoma es preparado por el método de gradiente iónico.